Main physical and chemical characteristics: brown color the oboyevypukly tablets covered with a sugar cover;
Structure. 1 tablet contains:
vitamin A (Retinolum acetate of BP)
B1 vitamin (thiamin nitrate of BP)
B2 vitamin (Riboflavinum of BP)
B6 vitamin (pyridoxine hydrochloride of BP)
B12 vitamin (cyanocobalamine of BP)
D3 vitamin (cholecalciferol of BP)
vitamin E (alpha tocopherol acetate of BP)
nikotinamida of BP
folic acid of BP
0, 1 mg
calcium of pantothenate of BP
2, 5 mg
USP ascorbate sodium,
40 mg of ascorbic acid are equivalent;
other components: sucrose, acacia pitch, methylparaben, propylparaben, sodium hydroxide, K-30 polyvinylpirrolidone, gelatin, liquid glucose (825), dinatrium edetat, ordinary milk bleach, cocoa powder, molokopodobny mix (Milkmaid), sodium saccharin, the connecting cellulose, fragrance vanilla, fragrance chocolate, silicon dioxide colloid (Aerosil 200), the purified talc, magnesium stearate, ordinary sugar, a white varnish, a brown varnish, caramel fragrance, karnaubsky wax, beeswax.
Form of production of medicine. Chewable tablets.
Farmakoterapevtichesky group. A polyvitaminic complex without additives.
Code of automatic telephone exchange A11B A.
Pharmacological properties. Grovit – polyvitaminic drug in the form of the chewable tablets covered with a sugar cover with chocolate taste. Pharmacological properties of drug are caused by biological effects of the vitamins which are its part. Fat-soluble vitamin A exerts various impact on life activity of an organism, supporting a normality of skin and an epithelium of mucous membranes (including, healing of wounds activates processes), plays a role in processes of photoreception, contribution of adaptation of the person to darkness. Vitamin E has active antioxidant, immunomodulatory and radio tire-tread actions, and also shows vascular and tire-tread properties: normalizes a tone and permeability of a vascular wall. Vitamin E - the powerful regulator of processes reproduction: pregnancies, fetations, formations and functioning of a reproductive system. D3 vitamin plays especially important role in regulation of a mineral exchange in an organism, including, in ensuring normal maturing of a bone tissue and a current of a wide range of exchange and physiological processes in it. Vitamin C - takes part in regulation of oxidation-reduction processes, an exchange of carbohydrates and formation of hormones, an angenesis, regulation of permeability of capillaries and turning of blood, etc. Vitamins of group B (thiamin, Riboflavinum, a pyridoxine, cyanocobalamine, folic acid and nikotinamid) - participate in all types of an exchange, providing normal functional activity of nervous, cardiovascular, digestive and secretory systems, processes a hemopoiesis, etc.
Pharmacokinetics. At are made drug of Grovit the special technology of conversion which consists in transfer of fat-soluble vitamins A, D and E in a water-soluble form is used. Thanks to it absorption of these vitamins B a digestive tract is facilitated, especially persons with deterioration in processes have an absorption of fats and, including, fat-soluble vitamins B a small intestine.
Proceeding from composition multicomponent structure, effect of drug of Grovit is difficult cumulative action of its components therefore carrying out kinetic researches is impossible: together all components cannot be investigated by means of markers or bioresearches. From this reason it is impossible to identify also numerous metabolites of drug.
Indications to use. Treatment of a vitamin deficiency, and also for the prevention of development of symptoms of a hypovitaminosis at unbalanced or limited food, overfatigue, stresses, negative influences dovkillya, compensations of a vitamin deficiency at infectious diseases and during recovery. As fortifying drug at treatment after operative measures, during active growth and development of children or teenagers.
Way of use and dose. To children from 3 to 13 years on 1 tablet once a day. To adults and teenagers after 14 years on 1 tablet 2 times a day. The maximum dose – 2 tablets a day. Tablets need to be chewed at first, and then to swallow. Duration of a course of treatment of a vitamin deficiency is defined depending on weight of a hypovitaminosis.
Side effect. At reception of the offered mode of a dosage and duration of a course of administration of drug of Grovit side effects were not observed, however allergic reactions at hypersensitivity to drug components are possible.
Contraindications. Hypersensitivity to any of drug components, the hypervitaminosis is previously known.
Overdose. Nausea, vomiting. Therapy is symptomatic.
Features of use. At Grovit's reception, as well as other polyvitaminic drugs, the full-fledged proteinaceous diet is necessary that promotes their best assimilation and an exchange.
It is possible colourings of urine in yellow color which is completely safe factor and is caused by existence in Riboflavinum drug.
Interaction with other medicines. It is necessary to avoid concomitant long use with other medicines or biological additives which contain vitamins. Especially with those which contain fat-soluble vitamins (Retinolum, cholecalciferol, tocopherol) through an overdose insecurity.
Terms and storage conditions. To store in the unavailable to children, dry, protected from light place, at a temperature of +8 °C - +15 °C. Not to keep in the refrigerator, not to freeze.