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Gastrozepin

Gastrozepin. Gastrozepinum. Pirenzepindi hydrochlorid.

5,11 - Digidro-11 - [(41 methyls-1 - piperazinit) acetyl] - 6H-pirido [2, Zb] [1,4]-benzodiazepin-6-0N.

Form of release of medicine. Tablets on 0,025 g, ampoules on 0,01 g of dry matter.

Use and doses of drug. Inside on 2 tablets of a gastrozepin 2 times a day; intramusculary or intravenously on 0,01 — 0,02 g in the form of freshly cooked solution each 12 h. In initial stages of diseases combine intake with parenteral administration from calculation: 2 doses inside, 1 — intramusculary. Course of treatment 4 weeks. At Zollinger's illness — Ellisona intravenously on 0,02 g, in hard cases 3 times a day.

Effect of the medicine. Gastrozepin - specific blocker M-holinoretseptorov of obkladochny and main cells of a mucous membrane of a stomach.

Indications to use. Stomach ulcer, gastritis, giperatsiditas, a duodenum ulcer, Zollinger's syndrome — Ellisona.

Contraindications. Glaucoma, a prostate hypertrophy (see Atropini sulfas). Pregnancy first 3 months.

Possible by-effects. Appetite strengthening, dryness in a mouth, vision disorders.

Treatment of complications and poisonings. See Atropini sulfas.

 
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