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Disturbance of an intestinal biocenosis at children and teenagers
Problems of a disbioz and methods of its correction
The quantity of the microbic cells which are present at skin and mucous a macroorganism, contacting to external environment exceeds number of cells of all its bodies and fabrics combined. The weight of microflora of a human body averages - 2,5-3 kg. Symbiotic associations of microflora of skin, an eye, an oral cavity, respiratory tracts, the urogenital sphere, a digestive tract have exclusive value in forming and functioning of various bodies and systems at the expense of products of various metabolites, enzymes, vitamins, biologically active agents, antigens and other connections which are formed in process of microbiological transformation of products ekzo-and an endogenous origin. The term "eubioz" is understood as a condition of a dynamic equilibrium which is defined, on the one hand, by physiological and immunobiological features of an organism of the owner, and with another - species and quantitative composition of microbic associations and a variety of their biochemical activity. Changes of a ratio of normal microflora can be both short-term - disbakterialny reactions, and resistant - dysbacteriosis. Under the term "dysbacteriosis" it is considered to be the permanent quantitative and high-quality disturbance of indigenny microflora leading to activation opportunistic or atypical for this biotope (habitals of microorganisms) of microorganisms.
I.I. Mechnikov who assumed that various metabolites and toxins produced by various microorganisms occupying bodies and systems of a human body are the reason of many diseases for the first time paid attention to value of microbic flora for the healthy person in 1914.
The problem of dysbacterioses causes many discussions with the extreme range of judgments in recent years. Acknowledging the possibility of existence of such morbid condition as dysbacteriosis ("disbioz", "a microecological imbalance", "a syndrome of excess growth of bacteria") from the clinical point of view dysbacteriosis is not considered as independent nosological unit. It is considered as the secondary morbid condition, a difficult symptom complex reflecting disturbance of a dynamic equilibrium between the macroorganism and its microflora accompanying various pathological processes and burdening their current.