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Degidroemetin

The archive section for reference information on the rare, being issued earlier, etc. medicines. On use of specific drug it is necessary to consult at the doctor!

Degidroemetin — Dehydroemetin
It is developed in Switzerland.
DAMIETING
Structure. Dihydrochloride of a 2-degidroemetin.
Effect of the medicine. Degidroemetin possesses amebotsidny activity and is much less toxic, than emetine.
Indications. Intestinal (all forms of acute and chronic amoebic colitis, including amoebic dysentery) and an abenteric amebiasis (amoebic hepatitis, liver abscess). Damages of lungs and skin. Treatment of an urinogenital schistosomiasis, bilgartsioz if other drugs cannot be used or they are inefficient; other trematodoza.
Use. Drug is appointed at the rate of 1 mg/kg of body weight a day within 6 — 10 days. Usually adults apply on 1 — 2 (10 — 20 mg) a dragee 3 times a day or to them enter 1 ampoule (60 mg) a day intramusculary. At a medium-weight current of an intestinal amebiasis appoint 1 dragee 3 times a day, at heavy disease increase a dose to 180 mg a day.
At treatment of a bilgartsioz the daily dose of drug makes 1,5 mg on 1 kg of body weight which is accepted within 10 days. The repeated course of treatment can be carried out only in 45 days.
Contraindications. Drug is appointed carefully to the pregnant, weakened and elderly people.
Side effect. Pains in the place of an injection, diarrhea, changes on an ECG (flattening of a tooth of T, decrease in an interval S — T).
Form of release of medicine. A dragee on 10 mg; ampoules on 1 and 2 ml (30 and 60 mg).

 
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