Beginning >> Drugs >> Subcategories >> System, antibacterial >> Cefaloridinum

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Cefaloridinum

Cefaloridinum. Cefaloridinum. Ceporinum. Ceflonn. Ceporan. Keflordin. Cefaloridine.

Salt of a betaine and 7-(2 thienylacetamidoes)-3-(1 pyridylmethyl) - 3-tsefem-4-carboxylic acid.

Form of release of medicine. Bottles with powder on 0,25, 0,5 and 1 g.

Use and doses of drug. Intramusculary or intravenously (within 3 — 5 min.) on 0,04 — 0,1 g on 1 kg of body weight a day. The daily dose is entered into 2 — 3 receptions. At an infection of urinary tract enter 0,015 — 0,03 g on 1 kg of body weight a day. Solutions are prepared before an injection. For intramuscular introduction dissolve 2 g in 4 ml, 1 g in 2,5 ml, 0,5 g in 2 ml and 0,25 g in 1 ml of water for injections. For intravenous administration of 0,5 — 1 g of the drug dissolved in 2 — 2,5 ml of water in addition part in 10 — 20 ml of isotonic solution of sodium of chloride (0,9%) or glucose (5%). Locally in a cavity: in pleural and belly on 0,25 g; intratekalno — on 0,05 g in 2 — 10 ml of isotonic solution of sodium of chloride. The newborn appoint at the rate of 0,015 g/kg, to children of advanced age of 0,02 — 0,03 g/kg a day.

The highest daily dose of 6 g.

Effect of the medicine. Cefaloridinum - a semi-synthetic antibiotic with a wide range of antimicrobic action, malotoksichen. It is active in relation to leptospira, spirochetes and staphylococcus producing penicillin. Does not influence mycobacteria of tuberculosis, proteas, shigellas, salmonellas, brucellas, rickettsiae, viruses. Cefaloridinum is badly soaked up at intake, slowly gets into cerebrospinal fluid. It is allocated with kidneys and bilious ways.

Indications to use. Pneumonia, the lung abscess, bronchitis, an empyema, a septic endocarditis, thrombophlebitis, meningitis, a cholangitis, cholecystitis, an angiocholitis, sepsis, abscess, phlegmon, osteomyelitis infected fractures of bones, purulent wounds and ulcers, pyelonephritis, a pyelitis, cystitis, prostatitis, mastitis, an adnexitis, pyodermas, a furunculosis, empitiginozny eczema, tonsillitis, otitis, sinusitis, antritis, a mastoiditis.

Contraindications. A serious illness of kidneys with disturbance of secretory function. Allergy.

Possible by-effects. Allergic reactions; in urine hyaline cylinders and other cellular elements, disturbance of secretory function of kidneys.

Treatment of complications and poisonings. See Benzilpenitsillin sodium salt.

 
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