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The Antitrombotichesky means applied in treatment of patients with coronary heart disease

The Antitrombotichesky means applied in treatment of patients with coronary heart disease (it is adapted from Sabatine MJS., Antmann eat., 2003).

Antithrombocytic drugs

Anticoagulants

Thrombolytic drugs

I. Aspirin + ++
II. Thienopyridinic drugs (antagonists of ADF):
• Klopidogrel (Plaviks *) + ++
• Tiklopidin (Tiklid *, Ipaton *) ++
• Prasugrel #
III. Antagonists of receptors of thrombocytes of GP IIb/IIIa:
• Absiksimab (ReoPro) +
• Eptifibatid (Integrilin) +
• Tirofiban (Aggrastat) +

I. Heparins
1a. Unfractionated heparin +
lb. Nizkoyomolekulyarny heparins:
• Enoksaparin
(kleksan *, lovenoks) +
• Dalteparin (fragmin *) +
II. The selection inhibitors Ha coagulation factor
• Fondaparinuks (Arixtra) #
III. Direct inhibitors of thrombin:
• Hirudine +
• PEG hirudine +
• Bivalirudin (girulog) +
• Argatroban #
IV. Peroral anticoagulants:
Warfarin * ++

I. Fibrinnespetsificheskiye:
Streptokinasa * +
II. Fibrinspetsificheskiye:
• Alteplaza * +
• Tenekteplaza * +

Notes: * - are available in broad practice in Russia;
+ - are applied at an acute coronary syndrome; ++ - are applied at chronic forms of coronary heart disease;
# - new antitrombotichesky drugs

 
"Adynamic zone of heart   Apoptosis at chronic heart failure"