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Vukhererioz and brugioz

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Vukhererioz and brugioz
Clinic of a vukhererioz
Clinic of a brugioz

Vukhererioz and brugioz - the diseases developing as a result of infection of Brugia malayi and Wuchereria bancrofti are clinically shown equally. At early stages the lymphangitis and acute lymphadenitis, at late stages — obstruction of lymphatic ways and to the gidrotsela are characteristic of them. According to indicative data, more than 200 million residents of developing countries have these helminthoses.
Vukhererioz (Latin — wuchereriosis; English — bancroftian filariasis) — a filariasis of lymphatic system. The incubation interval makes 3,5 — 12 months (approximately corresponds to time necessary for maturing of the invasive larvae which got to an organism to puberal forms and the birth them microfilarias).
Etiology. Larvae of filarias get into a human body at stings of mosquitoes together with saliva. Time of maturing of filarias proceeds within several months — 1 years. Lymphatic system becomes the place of continuous parasitizing. Puberal females produce a large number of the larvae circulating in the patient's blood. A life cycle of a parasite comes to the end in an organism of the mosquito which soaked up together with blood of a larva.
Epidemiology. In endemic areas more than 80% of the population are infected with filarias, but the clinical symptomatology is shown at only 10 — 20% from them. The persons working in the places abounding with the infected mosquitoes and which are not protected from their stings are exposed to the greatest danger. The disease often occurs among the population of acervate suburbs living in unsatisfactory sanitary conditions.
Ipfektion is extended by W. bancrofti in tropical and subtropical Africa and South America, and V. of malayi — in Southeast Asia and the southern regions of the Pacific Ocean.
Clinical manifestations. The acute period of a disease is followed by the fever periods, a lymphangitis on extremities, the headaches and mialgiya proceeding within several days — several weeks. Most often the symptomatology is observed at young people at the age of 10 — 20. Chronically proceeding infection like gidrotsel and elephantiasis occurs mainly at persons aged 30 years are more senior and represents result of fibrosing of lymph nodes and obstruction of lymphatic ways. Circulation of larvae (microfilarias) in blood is not followed by any pathological phenomena.
Diagnosis and treatment. Detection of microfilarias in blood — the only diagnostic method of a limfozhelezisty filariasis. For this purpose take 10 ml of blood, filter it and mikroskopirut. Capture of blood is dated by the time of the greatest number of parasites in blood, various in certain geographical conditions and depending on a type of filarias.
Indications to chemotherapy are individual. Specific treatment is not followed by effect at the senior citizens with the developed obstruction of lymphatic ways and also continuing to live in the endemic area. Patients of young age with acute displays of a disease and a lymphangitis should be treated dietilkarbamaziny on 50 mg in the 1st day once, on 50 mg twice in the 2nd day and on 50 mg three times in the 3rd day. Then up to the 21st day treatment is carried out by 10 mg of drug.



 
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