Papilloma — the high-quality new growth developing from a flat or transitional epithelium and acting over its surface in the form of nipples.
It is observed at any age, but a thicket at elderly persons.
Classification of papilloma
According to the WHO classification allocate papillomas of not virus etiology — a fibroepitelialny polyp (akrokhord) and a virus etiology — a wart an ordinary, bottom condyloma, a flat condyloma and a sharp-pointed condyloma.
Etiology and pathogeny
Papilloma represents a reactive hyperplasia of epidermis on action of one of types of a virus of papilloma of the person.
Clinical signs and symptoms
Papilloma is localized mainly on a neck, in natural folds or on a trunk and has an appearance of the single or multiple, sometimes grouped exophytic outgrowths, usually on narrower basis, with a smooth or fleecy surface, an elastic consistence, the sizes 0,3 — 0,5 cm (larger educations meet less often), various coloring — from light brown to various shades of gray color. Occasionally single elements can be presented by small knots of rounded shape on the wide basis. The hyperkeratosis, sometimes considerable is characteristic of viral papillomas. In the presence the patient of an immunodeficiency can have extremely big quantity of papillomatous elements.
The diagnosis and the recommended clinical trials
The diagnosis is made on the basis of clinical manifestations and data of a biopsy. Interpapillary growths of the high-differentiated multilayer flat epithelium with preservation of a lane of layers are characteristic of a pathomorphologic picture. Sometimes cells of a basal layer of a giperpigmentirovana, and the corneous layer can be sharply reinforced (keratopapilloma). In the thickness of epidermal tyazhy the keratinization centers, places can meet forming of pseudo-horn cysts. The stroma of education is provided by connecting fabric with various number of vessels.
Differential diagnosis of papilloma is carried out with a melanotsitarny nevus.
General principles of treatment
Are applied electro-, krio-, laser, a himiodestruktion with obligatory protection by the zinc paste surrounding skin. At diffusion defeats and suspicion on an immunodeficiency research of the immunological status of the patient is necessary.