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Clinical use of a proteflazid at herpesviridae infections

Table of contents
Clinical use of a proteflazid at herpesviridae infections
Characteristic of drug proteflazid
Treatment of a herpesviridae infection (type 1 - a herpes simplex)
Treatment of a herpesviridae infection (type 2 - a herpes simplex)
Treatment of a herpesviridae infection (type 3)
Treatment of a herpesviridae infection (type 4-Epstein-Barre's virus)
Treatment of a herpesviridae infection (type 5-tsitomegalovirusny infection)
Treatment of a herpesviridae infection (type 6)
Treatment of a herpesviridae infection (types 7-8)
Farmakoekonomichesky aspects of use of drug proteflazid

Herpesviridae infections belong to the most widespread viral infections on the globe. According to WHO data about 80-90% of the population on the globe are infected with one or several types of gerpesvirus. Now the Herpesviridae family totals more than 100 representatives from whom for the person the greatest pathogenicity viruses of a herpes simplex of 1-and 2 types (VPG-1, VPG-2), a virus of chicken pox or the virus of a varitsell zoster (VVZ), a cytomegalovirus (TsMV), the Epstein-Barre's virus (EBV), a virus of herpes of the person 6 like represent (VGCh-6), a virus of herpes of the person of the 7th type (VGCh-7), a virus of herpes of the person of the 8th type (VGCh-8).

The main biological and pathogenetic features of gerpesvirus are a long persistirovaniye in an organism of the infected person, a politropnost to various fabrics and ability to reactivation. These properties of gerpesvirus cause polymorphism of clinical manifestations,
defeat poliorgannost at generalized forms and high probability of transition of an infection to chronically recurrent. In the territory of Russia and other CIS countries not less than 22 million people have persistent herpesviridae infections, and recurrent forms of a persistent herpesviridae infection in the different countries are ill from 2 to 12% of people.

The problem of therapy of a herpesviridae infection continues to remain in the center of attention of doctors of different specialties. It is caused by annual increase in number of patients with these nosological forms, weight of disease, high probability of transition to chronic process with development of complications and an invalidism of patients, and also high cost of treatment. Search of drugs and schemes of therapy which would be continues not only are effective and safe, even at prolonged use, but also are available at cost for a wide range of patients.

In the made methodical recommendations to yours schemes of therapy of herpesviridae infections in which such factors as virus type, character and duration of disease were considered are presented. Each scheme is based on use of domestic antiviral drug PROTEFLAZID. This drug possesses the whole complex of pharmacological properties which allow not only to exponentiate action of standard antiviral therapy, but also to make treatment more available and safe, at the expense of a possible dose decline of chemical antiviral drugs.



 
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