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Glucagonoma

Glucagonoma etiology

In 70% of cases the malignant tumor, as a rule, exceeds in the diameter of 5 cm

Pathogeny

Hyperproduction of a glucagon, tumoral progression

Epidemiology

Meets casuistic seldom

Main clinical manifestations

The Nekrolitichesky migrating erythema, disturbance of tolerance to glucose, anemia, thromboembolisms, metastasises in a liver and other bodies

Diagnosis

T glucagon, topical diagnosis of a tumor

Differential diagnosis

The diabetes mellitus, level of a glucagon can be raised at a chronic renal and liver failure, acute pancreatitis, sepsis, etc.

Treatment

Radical operational treatment, as a rule, is impossible. Anti-proliferative therapy oktreotidy

Forecast

Bad

 
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