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Gemangioperitsitoma

Gemangioperitsitoma — a vascular tumor in which there is a proliferation of pericytes to formation of perivascular couplings.

Epidemiology

The rare tumor, arises at any age, a thicket at middle-aged persons, with an identical frequency at men and women.

Classification

• Angioperitsitoma are adult
• Angioperitsitoma of children.
Tumors have an identical morphological structure, however various forecast.

Etiology and pathogeny

Are studied insufficiently.

Clinical signs and symptoms

The tumor is localized mainly on head skin and extremities, in a hypodermic fatty layer and skeletal muscles of the lower extremities.
It is shown in the form of hilly knotty educations, usually solitary, various size and density covered with not changed or cyanotic-red skin. The tumor grows rather slowly, can ulcerate. Allocate 2 options of a current — high-quality and malignant from 50% with probability of metastasises.

The diagnosis and the recommended clinical trials

The biopsy is necessary for statement of the diagnosis.
The basis of a tumor is made by neogenic capillaries with slit-like, scarcely noticeable gleams. Tumor cells approximately identical, remind pericytes by outward, have the weak and eosinophilic cytoplasm containing the glycogen and roundish or oval kernels filled with euchromatin with a clear nuclear envelope. Mitoses meet seldom. When processing cuts silver salts in a tumor find the argyrophil fibers surrounding gleams of vessels and separating endothelial elements from the proliferating pericytes. In certain cases at such processing each cell of a tumor is surrounded with a thin argyrophil network that has diagnostic value. Proliferation of cells of a tumor is observed around vessels, mainly muftoobrazno.
In a gemangioperitsitoma of malignant option, as well as in metastasises, cells usually polymorphic, with dominance among them spindle-shaped forms; the large number of mitoses is noted. The tumor stroma a scanty, argyrophil network though is available, but without characteristic arrangement that complicates diagnosis.

Differential diagnosis

Glomusangioma, malignant fibrous histiocytoma, synovial sarcoma, mesenchymal chondrosarcoma.

General principles of treatment

Surgical excision is necessary.

Forecast

Children have a current of a gemangioperitsitoma more favorable.

 

 
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